US 7,579,005 B2
	Process for recombinant expression and purification of antimicrobial peptides using periplasmic targeting signals as precipitable hydrophobic tags
Sharon Jo Keeler, Bear, Del. (US); Sheryl M. Wolstenholme, Elkton, Md. (US); Jodie L. Duke, Newark, Del. (US); and Linda L. Hnatow, Oxford, Pa. (US)
Assigned to E. I. du Pont de Nemours and Company, Wilmington, Del. (US)
Filed on Nov. 28, 2005, as Appl. No. 11/287,809.
Prior Publication US 2007/0122425 A1, May 31, 2007
Int. Cl. A61K 39/00 (2006.01); A61K 39/38 (2006.01); A61K 39/085 (2006.01)

U.S. Cl. 424—192.1  [424/9.1; 424/9.2; 424/93.2; 424/184.1; 424/200.1; 424/234.1; 424/278.1; 424/282.1; 435/41; 435/69.8]

10 Claims

1. A composition comprising a fusion protein comprising a periplasmic targeting signal and at least one antimicrobial peptide.