US 7,413,548 B2
Autonomic nervous activity monitor, blood processing apparatus, blood collecting apparatus and autonomic nervous activity monitoring method
Kenji Tadokoro, Nagareyama (Japan); Fumiko Saitou, Sagamihara (Japan); and Yoshiki Takagi, Fuji (Japan)
Assigned to Japanese Red Cross Society, Minato-Ku, Tokyo (Japan); and Terumo Kabushiki Kaisha, Shibuya-Ku, Tokyo (Japan)
Filed on Mar. 18, 2005, as Appl. No. 11/83,213.
Claims priority of application No. 2004-081617 (JP), filed on Mar. 19, 2004.
Prior Publication US 2005/0209522 A1, Sep. 22, 2005
Int. Cl. A61B 5/02 (2006.01)
U.S. Cl. 600—500  [604/4.01; 604/66] 6 Claims
OG exemplary drawing
 
1. An autonomic nervous activity monitoring method for predicting whether abnormal reaction may occur to a body, comprising the steps of:
measuring heartbeat or pulse of a body to acquire a pattern of the heartbeat or pulse as biological information;
calculating a value [msec2] of a high frequency component (a HF value) defined as an indicator for parasympathetic activity and a value of a ratio of a low frequency component (LF) to the high frequency component (a LF/HF ratio value) defined as an indicator for sympathetic activity on a time-series base by carrying out frequency analysis to the acquired pattern of the heartbeat or pulse; and
predicting whether abnormal reaction may occur to the body from a predetermined relationship between the HF value and the LF/HF ratio value, based upon the calculated HF values and the calculated LF/HF ratio values;
wherein, when alpha is defined as a predetermined coefficient, the predicting step predicts that abnormal reaction may occur to the body when the calculated HF value exceeds a predetermined reference value, and, when a sum of a period of {(the calculated HF value)>(the coefficient alpha)×(the calculated LF/HF ratio value)} becomes not less than 10% of a calculation period in the calculating step.