US 7,576,184 B2
	Allergenic proteins of natural rubber latex, their production and use in assays
Mary Jane Cardosa, Penang (Malaysia); Hamid Sharifah, Penang (Malaysia); Shirley Samuel-Verghese, Kuala Lumpur (Malaysia); Elumalai Sunderasan, Kuala Lumpur (Malaysia); Hoong Yeet Yeang, Kuala Lumpur (Malaysia); and Hamzah Samsidar, Kuala Lumpur (Malaysia)
Assigned to The Board of the Rubber Research Institute of Malaysia, Kuata Lumpur (Malaysia); and Universiti Sains Malaysia, Kuala Lumpur (Mali)
Filed on Apr. 08, 2004, as Appl. No. 10/819,920.
Application 10/819920 is a division of application No. 08/529152, filed on Sep. 15, 1995, granted, now 6,759,517.
Claims priority of application No. PI 9402468 (MY), filed on Sep. 16, 1994; and application No. PI 9501205 (MY), filed on May 04, 1995.
Prior Publication US 2005/0043518 A1, Feb. 24, 2005
Int. Cl. C12P 21/08 (2006.01)

U.S. Cl. 530—387.1  [530/388.1]

3 Claims

1. An isolated monoclonal antibody developed against an allergenic protein from the latex or tissue of Hevea brasiliensis (Hev b), or allergenic sub-units or aggregates thereof, wherein said protein is allergenic protein Hev b IV which is oligomeric and consists of three major species of monomeric polypeptides with molecular weights 50, 55 and 57 kDa that are disulphide-linked into dimers of approximate molecular weights 100, 110 and 115 kDa.