US 7,575,758 B2
	Acaricidal compositions and methods of use thereof
Glenn F. King, Simsbury, Conn. (US); Ashis K. Mukherjee, Assam (India); Stephen K. Wikel, Unionville, Conn. (US); and Brianna Sollod McFarland, Fenton, Mo. (US)
Assigned to The University of Connecticut, Farmington, Conn. (US)
Filed on Sep. 13, 2006, as Appl. No. 11/520,384.
Claims priority of provisional application 60/717958, filed on Sep. 16, 2005.
Prior Publication US 2007/0066529 A1, Mar. 22, 2007
Int. Cl. A01N 63/00 (2006.01); A61K 38/17 (2006.01); C07K 14/435 (2006.01)

U.S. Cl. 424—405  [514/12; 530/324]

10 Claims

1. A method of controlling acarine pests, comprising applying an effective amount of an isolated polypeptide, or a composition comprising an isolated polypeptide to a locus of the acarine pests, wherein the polypeptide is an omega-ACTX peptide having greater than or equal to 70% sequence identity to SEQ ID NO: 1; capable of forming three intrachain disulfide bonds; and having six conserved cysteine residues at positions corresponding to amino acid positions 4, 11, 17, 18, 22 and 36 of SEQ ID NO:1.