US 11,718,877 B2
Methods for use in the diagnosis of autoimmune diseases
Hakon Hakonarson, Malvern, PA (US); Yun Rose Li, Philadelphia, PA (US); and Brendan Keating, Philadelphia, PA (US)
Assigned to THE CHILDREN'S HOSPITAL OF PHILADELPHIA, Philadelphia, PA (US)
Filed by The Children's Hospital of Philadelphia, Philadelphia, PA (US)
Filed on Aug. 20, 2019, as Appl. No. 16/545,469.
Application 16/545,469 is a continuation of application No. 15/242,091, filed on Aug. 19, 2016, granted, now 10,385,398.
Claims priority of provisional application 62/320,400, filed on Apr. 8, 2016.
Claims priority of provisional application 62/208,383, filed on Aug. 21, 2015.
Prior Publication US 2020/0080152 A1, Mar. 12, 2020
Int. Cl. C12Q 1/6883 (2018.01)
CPC C12Q 1/6883 (2013.01) [C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01)] 8 Claims
 
1. A method for detecting a T allele in a single nucleotide variation (SNV) in rs77150043 on 16q12.1 in ADCY7 in a Crohn's disease (CD) or psoriasis (PS or PSOR) human patient, the method comprising:
a) obtaining a biological sample from the human patient; and
b) detecting in a nucleic acid from the sample a T allele in SNV rs77150043 on 16q12.1 in ADCY7 by contacting the sample with a probe specific for said SNV and detecting binding between said probe and said SNV.