US 11,718,649 B2
Dimeric and trimeric proteins based on the FimH, CsgA, and PapG adhesins of uropathogenic Escherichia coli
Juan Xicohtencatl Cortes, Mexico City (MX); and Victor Manuel Luna Pineda, Mexico City (MX)
Assigned to HOSPITAL INFANTIL DE MÉXICO “FEDERICO GÓMEZ”
Appl. No. 16/754,118
Filed by HOSPITAL INFANTIL DE MÉXICO “FEDERICO GÓMEZ”, Mexico City (MX)
PCT Filed Oct. 11, 2018, PCT No. PCT/MX2018/000105
§ 371(c)(1), (2) Date Apr. 6, 2020,
PCT Pub. No. WO2019/074352, PCT Pub. Date Apr. 18, 2019.
Claims priority of application No. MX/a/2017/013104 (MX), filed on Oct. 11, 2017.
Prior Publication US 2020/0369732 A1, Nov. 26, 2020
Int. Cl. C07K 14/245 (2006.01); C07K 1/14 (2006.01); C12N 15/62 (2006.01)
CPC C07K 14/245 (2013.01) [C07K 1/14 (2013.01); C12N 15/62 (2013.01)] 13 Claims
 
1. A fusion protein characterized in that it includes a FimH adhesin covalently linked to a PapG and CsgA adhesins of uropathogenic Escherichia coli (E. coli), which comprises or consisting of SEQ ID NO: 2.