CPC C07D 471/04 (2013.01) | 8 Claims |
1. A compound represented by formula (I), or a pharmaceutically acceptable salt, prodrug, crystal form, stereoisomer, hydrate or solvate thereof:
wherein,
R1, R2, R3, R4, R5, R6, R7, and R8 are hydrogen;
R9 and R10 are deuterium;
R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, R25, R26, R27, R28, R29 R30, R31, R32, R33, R34, R35, R36, R37, R38, R39 and R40 are independently selected from hydrogen, deuterium, halogen and trifluoromethyl;
X1 and X2 are independently selected from the group consisting of hydrogen (H), deuterium (D), methyl, CH2D, CHD2, CD3, CH2CH3, CHDCH3, CHDCH2D, CHDCHD2, CHDCD3, CD2CH3, CD2CH2D, CD2CHD2 and CD2CD3;
the content of deuterium isotope in each deuterated position is at least greater than 50%.
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