| US 7,574,251 B2 | ||
| Method and system for adapting a radiation therapy treatment plan based on a biological model | ||
| Weiguo Lu, Madison, Wis. (US); Kenneth J. Ruchala, Madison, Wis. (US); Gustavo H. Olivera, Madison, Wis. (US); Eric Schnarr, McFarland, Wis. (US); Jeffrey M. Kapatoes, Madison, Wis. (US); Thomas R. Mackie, Verona, Wis. (US); and Paul J. Reckwerdt, Madison, Wis. (US) | ||
| Assigned to TomoTherapy Incorporated, Madison, Wis. (US) | ||
| Filed on Jul. 21, 2006, as Appl. No. 11/459,105. | ||
| Claims priority of provisional application 60/701580, filed on Jul. 22, 2005. | ||
| Prior Publication US 2007/0043286 A1, Feb. 22, 2007 | ||
| Int. Cl. A61B 5/05 (2006.01) | ||
| U.S. Cl. 600—427 [600/411] | 18 Claims |
| 1. A method of adapting a treatment plan, the method comprising:
preparing a treatment plan for a patient for treating a patient condition, the preparation including acquiring an internal
reference image of the patient;
acquiring three-dimensional internal images of the patient in substantially a treatment position;
performing deformable registration of the images;
acquiring data relating to a radiation dose delivered to the patient;
applying a biological model to relate the radiation dose delivered and a patient effect; and
adapting subsequent dose delivery of the treatment plan in a radiation delivery device based on the deformable registration
and the biological model.
|