US 7,572,888 B2
	Methods of assaying receptor activity and constructs useful in such methods
Lawrence S. Barak, Durham, N.C. (US); Marc G. Caron, Hillsborough, N.C. (US); Stephen S. Ferguson, London (Canada); and Jie Zhang, Wallingford, Conn. (US)
Assigned to Duke University, Durham, N.C. (US)
Filed on Feb. 24, 2004, as Appl. No. 10/785,841.
Application 10/785841 is a continuation of application No. 09/772644, filed on Jan. 30, 2001, granted, now 6,770,449.
Application 09/772644 is a continuation of application No. 09/469554, filed on Dec. 22, 1999, granted, now 6,528,271.
Application 09/469554 is a continuation in part of application No. 09/233530, filed on Jan. 20, 1999, granted, now 6,110,693, filed on Aug. 29, 2000.
Application 09/233530 is a continuation of application No. 08/869568, filed on Jun. 05, 1997, granted, now 5,891,646, filed on Apr. 06, 1999.
Prior Publication US 2004/0209308 A1, Oct. 21, 2004
Int. Cl. C07K 14/00 (2006.01); C07K 17/00 (2006.01); G01N 33/53 (2006.01); G01N 33/567 (2006.01)

U.S. Cl. 530—350  [435/7.1; 435/7.2]

9 Claims

1. A conjugate comprising a β-arrestin protein and a label, wherein said label is capable of indicating intracellular translocation and/or distribution of said β-arrestin protein, wherein said β-arrestin is capable of interacting with a G protein coupled receptor (GPCR).