US 7,572,440 B2
	Method for repairing a defect in an intervertebral disc
Slobodan Vukicevic, Zagreb (Croatia); Vladimir Katic, Zagreb (Croatia); and Kuber T. Sampath, Holliston, Mass. (US)
Assigned to Stryker Corporation, Kalamazoo, Mich. (US)
Filed on Apr. 03, 2007, as Appl. No. 11/784,111.
Application 11/192542 is a division of application No. 09/828607, filed on Apr. 06, 2001, granted, now 6,958,149.
Application 11/784111 is a continuation of application No. 11/192542, filed on Jul. 28, 2005.
Application 09/828607 is a continuation of application No. PCT/US99/17222, filed on Jul. 30, 1999.
Prior Publication US 2008/0167225 A1, Jul. 10, 2008
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 38/48 (2006.01)

U.S. Cl. 424—94.63  [424/93.7; 514/12; 514/2]

12 Claims

1. A method for repairing a defect in an intervertebral disc comprising the step of administering to the disc an effective amount of a composition comprising an osteogenic protein selected from the group consisting of OP-1 (osteogenic protein-1), OP-2, OP-3, BMP-2 (bone mohogenic protein-2), BMP-3, BMP-4, BMP-5, BMP-6, BMP-9, BMP-10, BMP-11, BMP-15, BMP-3B, DPP (decapentaplegic protein), Vg-1 (vegetal protein-1), Vgr-1 (murine vegetal protein-1), 60A protein, GDF-1 (growth differentiation factor-1), GDF-2, GDF-3, GDF-5, GDF-6, GDF-7, GDF-8, GDF-9, GDF-10 and GDF-11.