| US 7,572,376 B2 | ||
| Process for producing 1,3-propanediol | ||
| Avraham M. Baniel, Jerusalem (Israel); Robert P. Jansen, Collinsville, Ill. (US); Asher Vitner, Jerusalem (Israel); and Anthony Baiada, Dagenham (United Kingdom) | ||
| Assigned to Tate & Lyle Ingredients Americas, Inc., Decatur, Ill. (US) | ||
| Filed on Feb. 13, 2006, as Appl. No. 11/352,593. | ||
| Application 11/352593 is a continuation of application No. 10/430498, filed on May 06, 2003, granted, now 7,056,439. | ||
| Prior Publication US 2006/0124545 A1, Jun. 15, 2006 | ||
| Int. Cl. B01D 11/00 (2006.01); C07C 31/18 (2006.01) | ||
| U.S. Cl. 210—634 [210/639; 210/774; 210/806; 435/158; 568/868; 568/872] | 21 Claims |
| 1. A process for the recovery of 1,3-propanediol from a fermentation broth comprising 1,3-propanediol, comprising the steps
of:
contacting a fermentation broth that comprises greater than about 10 wt % water, about 5-85 wt % 1,3-propanediol, and about
5-70 wt % of at least one contaminant selected from glycerol, glucose, and butanetriol, with at least one solvent extractant
to form a first mixture, wherein the solvent extractant is selected from the group consisting of pentanol, propan-1-ol, hexanol,
oleyl alcohol, 4-methyl pentan-2-one, isopropyl acetate, tributyl phosphate, oleic acid, soya oil, castor oil, and combinations
thereof, and wherein the volume/volume ratio of solvent extractant to fermentation broth is between 1:4 and 50:1,
separating the first mixture into a first phase and a second phase,
wherein the first phase comprises a majority of the solvent extractant and at least some of the 1,3-propanediol that was present
in the fermentation broth, and the weight ratio in the first phase of 1,3-propanediol to at least one of glycerol, glucose,
or butanetriol is greater than the weight ratio of 1,3-propanediol to the same contaminant in the fermentation broth prior
to the fermentation broth being contacted with the solvent extractant,
wherein the second phase comprises a majority of the water and at least some of the contaminant from the fermentation broth,
recovering 1,3-propanediol by removing the first phase from the second phase,
contacting the removed first phase with a first quantity of aqueous solution to form a second mixture, wherein the volume
ratio of the first quantity of aqueous solution to the first phase is between about 20:1 and about 1:20, and
separating the second mixture into a third phase and a fourth phase,
wherein the third phase comprises a majority of solvent extractant of the first phase, and wherein the fourth phase comprises
1,3-propanediol and a majority of the first quantity of aqueous solution, the weight ratio in the fourth phase of the 1,3-propanediol
to at least one of glycerol, glucose, or butanetriol is greater than the weight ratio of 1,3-propanediol to the same contaminant
in the fermentation broth prior to the fermentation broth being contacted with the solvent extractant, and said contacting
and recovering steps result in the concentration of 1,3 propanediol in the fourth phase being over 99 wt % on a water-excluded
basis.
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