US 7,569,670 B2
Cytokine zalpha11 ligand fusion proteins
Julia E. Novak, Bainbridge Island, Wash. (US); Scott R. Presnell, Tacoma, Wash. (US); Cindy A. Sprecher, Seattle, Wash. (US); Donald C. Foster, Lake Forest Park, Wash. (US); Richard D. Holly, Seattle, Wash. (US); Jane A. Gross, Seattle, Wash. (US); Janet V. Johnston, Seattle, Wash. (US); Andrew J. Nelson, Shoreline, Wash. (US); Stacey R. Dillon, Seattle, Wash. (US); and Angela K. Hammond, Maple Valley, Wash. (US)
Assigned to ZymoGenetics, Inc., Seattle, Wash. (US)
Filed on Oct. 20, 2006, as Appl. No. 11/551,368.
Application 11/551368 is a division of application No. 10/787442, filed on Feb. 26, 2004.
Application 10/295723 is a division of application No. 09/923246, filed on Aug. 03, 2001, granted, now 6,605,272, filed on Aug. 12, 2003.
Application 09/923246 is a division of application No. 09/522217, filed on Mar. 09, 2000, granted, now 6,307,024, filed on Oct. 23, 2001.
Application 10/787442 is a continuation of application No. 10/659684, filed on Sep. 10, 2003.
Application 10/659684 is a continuation of application No. 10/295723, filed on Nov. 15, 2002, granted, now 6,686,178, filed on Feb. 03, 2004.
Claims priority of provisional application 60/142013, filed on Jul. 01, 1999.
Claims priority of provisional application 60/123904, filed on Mar. 11, 1999.
Claims priority of provisional application 60/123547, filed on Mar. 09, 1999.
Prior Publication US 2007/0066807 A1, Mar. 22, 2007
Int. Cl. C07K 17/00 (2006.01); C07K 14/00 (2006.01); A61K 39/00 (2006.01)
U.S. Cl. 530—351  [530/350; 424/185.1] 4 Claims
 
1. A fusion protein comprising a first polypeptide and a second polypeptide, wherein the first polypeptide comprises an amino acid sequence that is at least 90% identical to SEQ ID NO:2 from residues 41 to 148, and wherein the second polypeptide comprises SEQ ID NO:113 or fragment thereof; wherein the fusion protein binds a receptor comprising the amino acid sequence of SEQ ID NO:115.