CPC C07D 401/12 (2013.01) [A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/4709 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); C07D 213/72 (2013.01); C07D 213/73 (2013.01); C07D 213/82 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01)] | 26 Claims |
1. A method of treating a tumor in an individual diagnosed with cancer, comprising administering to the individual an effective amount of
4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyridin-4-ylamino)-N-(1,3-dihydroxypropan-2-yl)nicotinamide or a pharmaceutically acceptable salt thereof, wherein the cancer is selected from the group consisting of colon cancer, liver cancer, thyroid cancer, endometroid cancer, gallbladder cancer, kidney cancer, adrenocortical cancer, skin cancer, head and neck cancer and sarcoma.
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