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US 11,702,392 B2 |
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Pyrimidinone derivatives as SHP2 antagonists |
Catherine Jorand-Lebrun, Billerica, MA (US); Roch Boivin, Billerica, MA (US); Theresa Johnson, Billerica, MA (US); Yanping Wang, Billerica, MA (US); Yufang Xiao, Billerica, MA (US); Xiaoling Chen, Billerica, MA (US); Nina Linde, Darmstadt (DE); Doreen Musch, Darmstadt (DE); and Deepak Kumar, Billerica, MA (US) |
Assigned to Merck Patent GmbH, Darmstadt (DE) |
Filed by MERCK PATENT GMBH, Darmstadt (DE) |
Filed on Feb. 22, 2021, as Appl. No. 17/181,614. |
Application 17/181,614 is a continuation of application No. 16/843,735, filed on Apr. 8, 2020, granted, now 11,001,561. |
Claims priority of provisional application 62/879,816, filed on Jul. 29, 2019. |
Claims priority of application No. 19167897 (EP), filed on Apr. 8, 2019. |
Prior Publication US 2021/0179565 A1, Jun. 17, 2021 |
Int. Cl. C07D 239/36 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 471/10 (2006.01); C07D 487/10 (2006.01); C07D 491/052 (2006.01); C07D 491/107 (2006.01); C07D 491/20 (2006.01); A61P 35/00 (2006.01) |