US 11,701,656 B2
Multi-droplet capture
Dawen Cai, Ann Arbor, MI (US); Daniel Nunez, Ann Arbor, MI (US); Katsuo Kurabayashi, Ann Arbor, MI (US); and Meng-Ting Chung, Ann Arbor, MI (US)
Assigned to The Regents of the University of Michigan, Ann Arbor, MI (US)
Appl. No. 16/957,338
Filed by The Regents of the University of Michigan, Ann Arbor, MI (US)
PCT Filed Jan. 2, 2019, PCT No. PCT/US2019/012039
§ 371(c)(1), (2) Date Jun. 23, 2020,
PCT Pub. No. WO2019/136058, PCT Pub. Date Jul. 11, 2019.
Claims priority of provisional application 62/612,755, filed on Jan. 2, 2018.
Prior Publication US 2020/0330991 A1, Oct. 22, 2020
Int. Cl. B01L 3/00 (2006.01); C12Q 1/6874 (2018.01); G01N 1/28 (2006.01)
CPC B01L 3/502761 (2013.01) [B01L 3/502715 (2013.01); B01L 3/502792 (2013.01); C12Q 1/6874 (2013.01); G01N 1/28 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/12 (2013.01); B01L 2400/0415 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A system comprising:
a) a plurality of first droplets and a plurality of second droplets, wherein said second droplets are smaller than said first droplets;
b) a substrate comprising a plurality of trapping sites,
wherein each of said trapping sites is configured to trap one and only one of said first droplets, and
wherein each of said trapping sites is further configured to trap one and only one of said second droplets when a first droplet is present in said trapping site.