US 11,701,451 B1
Soft tissue filler and methods
Dean Allen Klein, North Oaks, MN (US); Eric A. Furlich, St. Louis Park, MN (US); and Jared Klein, Minneapolis, MN (US)
Assigned to Carbon Medical Technologies, Inc., St. Paul, MN (US)
Filed by Carbon Medical Technologies, Inc., St. Paul, MN (US)
Filed on Mar. 11, 2022, as Appl. No. 17/692,594.
Int. Cl. A61L 27/26 (2006.01); A61K 9/00 (2006.01); A61K 31/716 (2006.01); A61K 31/729 (2006.01); A61L 27/20 (2006.01)
CPC A61L 27/26 (2013.01) [A61K 9/0024 (2013.01); A61K 31/716 (2013.01); A61K 31/729 (2013.01); A61L 27/20 (2013.01); A61L 2430/34 (2013.01)] 19 Claims
 
1. A method of making a malleable soft tissue filler for use to fill a body cavity in the body of a mammal in which soft tissue has been removed to create the body cavity; the method of making a malleable soft tissue filler, comprising the steps of:
creating a mixture by mixing from about 0.5 percent by weight to about 2 percent by weight of a first cross-linking polysaccharide material and from about 0.01 percent by weight to about 0.3 percent by weight of a second cross-linking polysaccharide material with water for a sufficient time to form an aqueous suspension of both the first cross-linking polysaccharide material and the second cross-linking polysaccharide material; wherein the first cross-linking polysaccharide material is (1-3), (1-4) beta-D-glucan and wherein the second cross-linking polysaccharide material is agarose; and
lyophilizing the aqueous suspension.