	US 11,701,364 B2
	Agonists of stimulator of interferon genes sting
Luke L. Lairson, San Diego, CA (US); Emily Chin, San Diego, CA (US); Arnab K. Chatterjee, San Diego, CA (US); Manoj Kumar, San Diego, CA (US); Ana Maria Gamo Albero, La Jolla, CA (US); Hank Michael James Petrassi, San Diego, CA (US); Peter G. Schultz, La Jolla, CA (US); Chenguang Yu, La Jolla, CA (US); Junko Tamiya, Carlsbad, CA (US); William Vernier, Vista, CA (US); Anil Gupta, San Diego, CA (US); and Ramkumar Modukuri, Houston, TX (US)
Assigned to The Scripps Research Institute, La Jolla, CA (US)
Appl. No. 15/733,535
Filed by The Scripps Research Institute, La Jolla, CA (US)
PCT Filed Feb. 21, 2019, PCT No. PCT/US2019/018899 § 371(c)(1), (2) Date Aug. 21, 2020, PCT Pub. No. WO2019/165032, PCT Pub. Date Aug. 29, 2019.
Claims priority of provisional application 62/633,409, filed on Feb. 21, 2018.
Prior Publication US 2021/0205321 A1, Jul. 8, 2021
Int. Cl. A61K 31/5365 (2006.01); A61K 9/19 (2006.01); A61K 9/127 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/536 (2006.01); A61K 45/06 (2006.01); A61K 47/68 (2017.01); A61K 9/00 (2006.01)

CPC A61K 31/5365 (2013.01) [A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 9/127 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/536 (2013.01); A61K 45/06 (2013.01); A61K 47/6803 (2017.08)]

14 Claims

1. A method of stimulating expression of interferon genes, comprising administering to a patient an effective dose of a compound of any one of the following formulae:

or a pharmaceutically acceptable salt thereof.