US 11,701,217 B2
Composite scaffold for the repair, reconstruction, and regeneration of soft tissues
Kevin A. Rocco, New Haven, CT (US); Bhavana Mohanraj, Philadelphia, PA (US); Jeffrey Ott, New Haven, CT (US); Justin Bendigo, Reading, PA (US); Jacob Edward Komenda, New Haven, CT (US); Mark Theodore Aronson, Midlothian, VA (US); and Andrew James Carter, Stow, MA (US)
Assigned to Biorez, Inc., New Haven, CT (US)
Filed by Biorez, Inc., New Haven, CT (US)
Filed on Jun. 13, 2022, as Appl. No. 17/838,694.
Application 17/838,694 is a continuation of application No. 17/379,093, filed on Jul. 19, 2021, granted, now 11,357,613.
Application 17/379,093 is a continuation of application No. 16/785,529, filed on Feb. 7, 2020, granted, now 11,065,102, issued on Jul. 20, 2021.
Claims priority of provisional application 62/970,620, filed on Feb. 5, 2020.
Claims priority of provisional application 62/802,391, filed on Feb. 7, 2019.
Prior Publication US 2022/0362004 A1, Nov. 17, 2022
Int. Cl. A61F 2/08 (2006.01); A61L 27/24 (2006.01); A61L 27/52 (2006.01); A61L 27/18 (2006.01); A61L 27/56 (2006.01); A61F 2/00 (2006.01); A61L 27/48 (2006.01); D06N 3/00 (2006.01); A61L 27/14 (2006.01); A61L 27/26 (2006.01); A61L 27/58 (2006.01); A61L 27/34 (2006.01); A61L 27/50 (2006.01); D04B 21/12 (2006.01)
CPC A61F 2/08 (2013.01) [A61F 2/0063 (2013.01); A61L 27/14 (2013.01); A61L 27/18 (2013.01); A61L 27/24 (2013.01); A61L 27/26 (2013.01); A61L 27/48 (2013.01); A61L 27/52 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); D06N 3/0043 (2013.01); A61F 2002/0068 (2013.01); A61F 2002/0081 (2013.01); A61F 2210/0004 (2013.01); A61F 2210/0057 (2013.01); A61F 2210/0061 (2013.01); A61F 2210/0076 (2013.01); A61F 2240/001 (2013.01); A61L 27/34 (2013.01); A61L 27/50 (2013.01); A61L 2430/10 (2013.01); D04B 21/12 (2013.01); D10B 2509/08 (2013.01); Y10T 428/249921 (2015.04); Y10T 428/249978 (2015.04); Y10T 442/2484 (2015.04); Y10T 442/419 (2015.04)] 13 Claims
OG exemplary drawing
 
1. A method of making a composite scaffold comprising:
A) constructing a three-dimensional support structure by knitting a scaffold comprising first and second layers spaced apart to define an interior space therebetween but attached together by a plurality of spacer elements extending through the interior space, the support structure extending along a length dimension between first and second ends thereof; and
B) forming a microporous matrix within the interior space, the microporous matrix having a multitude of interconnected pores in fluid communication with exterior surfaces of the support structure,
wherein a plurality of the interconnected pores are oriented relative to a dimensional characteristics of the support structure.