US 11,701,022 B2
Method for calibrating a bioimpedance measuring device, and medical devices
Ulrich Moissl, Karben (DE); Paul Chamney, Tring (GB); Tobias Groeber, Heusenstamm (DE); and Peter Wabel, Hosbach (DE)
Assigned to Fresenius Medical Care Deutschland GmbH, Bad Homburg (DE)
Filed by Fresenius Medical Care Deutschland GmbH, Bad Homburg (DE)
Filed on Jan. 6, 2020, as Appl. No. 16/734,921.
Prior Publication US 2021/0204829 A1, Jul. 8, 2021
Int. Cl. A61B 5/053 (2021.01)
CPC A61B 5/053 (2013.01) [A61B 2560/0228 (2013.01); A61B 2560/0252 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A method for calibrating a bioimpedance measuring device, the method comprising the steps:
providing the bioimpedance measuring device;
providing a measuring standard with a plurality of components (X, Y, Z), that may each be adjusted in terms of their respective component value (x1, x2, . . . xm; yi, y2, . . . y; zi, z, . . . zo), so that a number |K| of combinations of component values may be set, wherein |K|=m*n*o;
providing a Patient Database with a number |PDB| combinations of information, wherein each of the combinations of information comprises:
a) one or more patient parameters that characterize a specific patient, wherein the one or more patient parameters are not bioimpedance measurement results; and
b) a plurality of bioimpedance measurement results of the specific patient from at least one previous bioimpedance measurement process of the specific patient measured over a frequency range;
determining a number |CDB| of the combinations of component values based on which the plurality of bioimpedance measurement results of at least a predetermined part of the number |PDB| of combinations of the information may be gained using Cole Models or Cole-Cole Plots, wherein the number |CDB| is less than the number |K|;
providing a Calibration Database or Pool comprising the determined number |CDB| of the combinations of component values; and
calibrating the bioimpedance measuring device by using the measuring standard and adjusting the plurality of components (X, Y, Z) to some or all of the number |CDB| of the combinations of component values from the Calibration Database or Pool, but not by adjusting the plurality of components (X, Y, Z) to more than the number |CDB| of the combinations of component values.