US 7,563,886 B2
Nucleoside releasing functional unit through oxidation and process for producing oligonucleotide containing thereof
Isao Saito, Kyoto (Japan); Akimitsu Okamoto, Kyoto (Japan); and Kazuo Tanaka, Kyoto (Japan)
Assigned to Japan Science and Technology Agency, Kawaguchi-shi (Japan)
Appl. No. 10/567,364
PCT Filed Aug. 02, 2004, PCT No. PCT/JP2004/011039
§ 371(c)(1), (2), (4) Date Feb. 07, 2006,
PCT Pub. No. WO2005/014610, PCT Pub. Date Feb. 17, 2005.
Claims priority of application No. 2003-289972 (JP), filed on Aug. 08, 2003.
Prior Publication US 2007/0270582 A1, Nov. 22, 2007
Int. Cl. C07H 19/22 (2006.01)
U.S. Cl. 536—27.13  [536/25.32; 536/27.1; 536/27.14] 7 Claims
 
1. A nucleoside, a nucleotide or an oligonucleotide, comprising:
a moiety represented by the following formula (I):

OG Complex Work Unit Drawing
wherein X and Y each represent —NH—;
wherein R represents a color-fluorescing unit, a reporter unit or a biofunctional molecule;
wherein R1 and R2 each represent a hydrogen atom, a phosphate bonding group, a phosphoramidite group or a nucleotide; and
wherein n is 2.