G is SO₂ or CO;

R₁, R₄, R₈, and R₉ are each, independently, H, Cl, Br, F, I, NO₂, alkyl, alkoxy, phenyl, OCF₃, CF₃, or CN;

R₂, R₃, R₅, and R₆ are each, independently, hydrogen, hydroxy, alkyl, alkoxy, or halogen;

or R₂ and R₅ may together form a ring, said ring being a 4 to 8 membered cycloalkane, cycloalkene, cycloalkyne, or aromatic ring optionally containing one or more heteroatoms;

R₇ is hydrogen, alkyl, —(C═O)R₁₆, —S(O)₂R₁₇, —S(O)₂N(R₁₈)(R₁₉), or D-glucuronidate;

R₁₀ and R₁₁ are each, independently, H, alkyl, cycloalkyl, or phenyl;

R₁₆ is alkyl, alkoxy, arylalkyl, or aryl;

R₁₇ is alkyl, aryl, heteroaryl, cycloalkyl, alkenyl, cycloalkenyl, or alkynyl;

R₁₈ and R₁₉ are, independently, hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, monofluoroalkyl, perfluoroalkyl, aryl, arylalkyl, cycloalkenyl, heteroaryl, heteroarylalkyl, hydroxy-(C₂-C₆)alkyl, alkoxyalkyl, alkylthioalkyl, carbonyl, acyl, alkoxycarbonyl, —C(O)NH₂, alkylaminocarbonyl, dialkylaminocarbonyl, alkylaminoalkyl, or dialkylaminoalkyl;

or R₁₈ and R₁₉ are taken together with the nitrogen atom to which they are attached to form a saturated, unsaturated or partially saturated C₄-C₆ carbon ring;

X is H, alkyl, CN, CHO, F, Br, Cl, CONR_XR_Y, COOH, CO₂R_z, or cycloalkyl; and

R_x, R_y, and R_z are each, independently, H or alkyl;

or a pharmaceutically acceptable salt thereof.