US 7,560,259 B2
	Glutathione S-transferase sequence variants
Richard M. Weinshilboum, Rochester, Minn. (US); Baidehi Mukherjee, Rochester, Minn. (US); Linda L Pelleymounter, Rochester, Minn. (US); Oreste Salavaggione, St. Louis, Mo. (US); and Eric D. Wieben, Rochester, Minn. (US)
Assigned to Mayo Foundation for Medical Education and Research, Rochester, Minn. (US)
Filed on Apr. 15, 2008, as Appl. No. 12/103,444.
Application 12/103444 is a division of application No. 11/482525, filed on Jul. 07, 2006, granted, now 7,390,894.
Claims priority of provisional application 60/697128, filed on Jul. 07, 2005.
Prior Publication US 2008/0248549 A1, Oct. 09, 2008
Int. Cl. C12N 9/10 (2006.01); C07K 14/00 (2006.01); C12P 21/00 (2006.01); C12N 15/00 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12Q 1/48 (2006.01); C07H 21/00 (2006.01)

U.S. Cl. 435—193  [435/320.1; 435/69.1; 435/325; 435/352.3; 435/15; 530/350; 536/23.2; 536/23.5]

2 Claims

1. An isolated glutathione S-transferase omega 2 (GSTO2) polypeptide, wherein said polypeptide comprises an amino acid sequence which differs from SEQ ID NO:9 solely by a modification selected from the group consisting of (a) an amino acid substitution at position 41 of SEQ ID NO:9, (b) an amino acid substitution at position 130 of SEQ ID NO:9, (c) an amino acid substitution at position 158 of SEQ ID NO:9, and (d) any combination of (a)-(c).