US 7,560,112 B2
	Anti-il-6 antibodies, compositions, methods and uses
Yan Chen, Wayne, Pa. (US); Debra Gardner, Bear, Del. (US); David M. Knight, Berwyn, Pa. (US); Michael W. Lark, Devon, Pa. (US); Bailin Liang, Gilbertsville, Pa. (US); David J. Shealy, Downingtown, Pa. (US); Xiao-Yu R. Song, West Chester, Pa. (US); Vedrana Stojanovic-Susulic, Princeton Junction, N.J. (US); Raymond W. Sweet, Bryn Mawr, Pa. (US); Susan H. Tam, Boothwyn, Pa. (US); Sheng-Jiun Wu, Broomall, Pa. (US); Jing Yang, Ambler, Pa. (US); David Matthew Marquis, Encinitas, Calif. (US); Eric Michael Smith, San Diego, Calif. (US); and Alain Philippe Vasserot, Carlsbad, Calif. (US)
Assigned to Applied Molecular Evolution, Inc., San Diego, Calif. (US); and Centocor Ortho Biotech Inc., Malvern, Pa. (US)
Filed on Apr. 28, 2006, as Appl. No. 11/413,561.
Prior Publication US 2006/0257407 A1, Nov. 16, 2006
Int. Cl. A61K 39/395 (2006.01); C07K 16/24 (2006.01); C12N 5/12 (2006.01)

U.S. Cl. 424—139.1  [530/388.23; 435/326]

16 Claims

1. An isolated IL-6 antibody, comprising a light chain variable region amino acid sequence of SEQ ID NO:97 and/or a heavy chain variable region amino acid sequence of SEQ ID NO:99.