| US 7,558,624 B2 | ||
| Apparatus for reverse iontophoresis and method for reverse iontophoresis | ||
| Mitsuhiro Nishio, Yokohama (Japan) | ||
| Assigned to Kabushiki Kaisha Toshiba, Tokyo (Japan) | ||
| Filed on Oct. 23, 2003, as Appl. No. 10/691,825. | ||
| Claims priority of application No. P2002-308574 (JP), filed on Oct. 23, 2002. | ||
| Prior Publication US 2004/0188256 A1, Sep. 30, 2004 | ||
| Int. Cl. A61N 1/30 (2006.01) | ||
| U.S. Cl. 604—20 | 9 Claims |
| 1. An apparatus for reverse iontophoresis configured such that it is contacted with a specimen comprising:
a base;
a conductive locating pin provided on the base;
an on-base electrode provided on the base;
an electrolytic gel provided on the on-base electrode adapted for contacting a first part of the specimen, and for extracting
a molecule from the first part of the specimen;
a sensor chip disposed on the base and underneath the electrolytic gel, the sensor chip comprising a chip base having a locating
hole, a pigment membrane disposed on the chip base and containing a pigment that changes color by reaction with the molecule,
an on-chip electrode being disposed over the locating hole and adapted for electrically connecting to the conductive locating
pin through the locating hole and for contacting a second part of the specimen;
a light source irradiating light on the pigment membrane through an observation opening in the chip base; and
a light sensor receiving a reflection of the light from the pigment membrane through the observation opening in the chip base.
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