US 7,557,106 B2
Substituted pyrimidines useful as protein kinase inhibitors
Jean-Damien Charrier, Grove Wantage (United Kingdom); Francesca Mazzei, Abingdon (United Kingdom); David Kay, Wiltshire (United Kingdom); and Andrew Miller, Upton (United Kingdom)
Assigned to Vertex Pharmaceuticals Incorporated, Cambridge, Mass. (US)
Filed on Aug. 09, 2006, as Appl. No. 11/500,981.
Application 11/500981 is a continuation of application No. 10/464430, filed on Jun. 18, 2003, abandoned.
Claims priority of provisional application 60/390658, filed on Jun. 20, 2002.
Claims priority of provisional application 60/411609, filed on Sep. 18, 2002.
Prior Publication US 2006/0270660 A1, Nov. 30, 2006
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 403/14 (2006.01); A61K 31/4155 (2006.01)
U.S. Cl. 514—252.19  [544/295] 12 Claims
 
1. A compound selected from the following Table 1 compounds, or a pharmaceutically acceptable salt thereof:
TABLE 1
 
No.  
V— Structure
 
 
1  
 
7  
 
11  
 
13  
 
14