US 7,553,932 B1
Methods of treating viral infection with IL-10 receptor antagonists
Matthias G. Von Herrath, Del Mar, Calif. (US); and Anne Mette Ejrnaes, San Diego, Calif. (US)
Assigned to La Jolla Institute for Allergy and Immunology, La Jolla, Calif. (US)
Filed on Apr. 25, 2006, as Appl. No. 11/411,222.
Claims priority of provisional application 60/674795, filed on Apr. 25, 2005.
Int. Cl. C07K 14/52 (2006.01); A61K 38/19 (2006.01)
U.S. Cl. 530—351  [424/85.1] 34 Claims
 
1. A method of treating a subject with an established or chronic arenavirus or a herpesvirus infection, comprising administering to a subject an amount of an IL-10 Receptor (IL-10R) antagonist sufficient to reduce arenavirus or herpesvirus titer.