| US 7,553,835 B1 | ||
| Topical antifungal composition | ||
| Greg Davey, Rowville (Australia); and Albert Zorko Abram, Rowville (Australia) | ||
| Assigned to Stiefel Research Australia Pty Ltd, Rowville (Australia) | ||
| Appl. No. 9/529,033 PCT Filed Oct. 19, 1998, PCT No. PCT/AU98/00867 § 371(c)(1), (2), (4) Date Apr. 05, 2000, PCT Pub. No. WO99/20250, PCT Pub. Date Apr. 29, 1999. |
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| Claims priority of application No. PO9838 (AU), filed on Oct. 17, 1997; and application No. PP1217 (AU), filed on Jan. 06, 1998. | ||
| Int. Cl. A61K 31/50 (2006.01); A01N 25/16 (2006.01) | ||
| U.S. Cl. 514—247 [424/1.13; 424/404; 514/863; 514/864; 514/945; 514/947] | 28 Claims |
| 12. A topical, foamable composition consisting essentially of:
(a) one or more antifungal agents selected from the group consisting of an imidazole compound and a triazole compound;
(b) at least one surfactant selected from the group consisting of a quaternary compound, ethoxylated sorbitan stearate, ethoxylated
sorbitan palmitate, ethoxylated sorbitan oleate, and mixtures thereof;
(c) a lower alcohol content of greater than 10% by weight;
(d) water;
(e) a long chain alcohol;
(f) hydrocarbon gas propellant in an amount of less than 60% by weight; and
wherein said composition is a temperature-sensitive, quick-breaking foam or mousse, and has a residual non-volatile component
content of less than 25% by weight.
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