US 7,553,630 B2
Methods for detecting metalloproteinase inhibitors
Keith E. Langley, Newbury Park, Calif. (US); Yves A. DeClerck, Los Angeles, Calif. (US); and Thomas C Boone, Newbury Park, Calif. (US)
Assigned to Amgen Inc., Thousand Oaks, Calif. (US); and Childrens Hospital Los Angeles, Los Angeles, Calif. (US)
Filed on Jul. 19, 2004, as Appl. No. 10/893,323.
Application 10/893323 is a division of application No. 08/803954, filed on Feb. 21, 1997, granted, now 6,849,450.
Application 08/803954 is a division of application No. 08/212660, filed on Mar. 11, 1994, granted, now 5,714,465.
Application 08/212660 is a continuation of application No. 08/087021, filed on Jul. 06, 1993, abandoned.
Application 08/087021 is a continuation of application No. 07/710728, filed on Jun. 03, 1991, abandoned.
Application 07/710728 is a continuation in part of application No. 07/501904, filed on Mar. 29, 1990, abandoned.
Application 07/501904 is a continuation in part of application No. 07/355027, filed on May 19, 1989.
Prior Publication US 2005/0196390 A1, Sep. 08, 2005
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 33/53 (2006.01); G01N 33/58 (2006.01); G01N 33/60 (2006.01); G01N 33/567 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01); G01N 33/537 (2006.01); G01N 33/577 (2006.01)
U.S. Cl. 435—7.21  [435/7.1; 435/7.23; 435/7.72; 435/7.92] 12 Claims
 
1. A method for detecting metalloproteinase inhibitor in a biological sample, comprising
contacting an antibody specifically binding to a polypeptide comprising an amino acid sequence of SEQ ID NO: 7 or SEQ ID NO: 9 with said biological sample; and
measuring the binding of the antibody to said polypeptide to detect metalloproteinase inhibitor.