US 11,680,078 B2
Anticancer compounds
Vitthal Yadav, Maharashtra (IN); Maithili Athavale, Maharashtra (IN); Prashant Kharkar, Maharashtra (IN); Sangeeta Srivastava, Maharashtra (IN); Samir Somaiya, Maharashtra (IN); Smera Satish, Maharashtra (IN); and Sandip Gavade, Maharashtra (IN)
Assigned to GODAVARI BIOREFINERIES LTD., Maharashtra (IN)
Filed by GODAVARI BIOREFINERIES LIMITED, Maharashtra (IN)
Filed on Jun. 30, 2021, as Appl. No. 17/364,570.
Application 17/364,570 is a continuation of application No. 16/336,460, granted, now 11,084,843, previously published as PCT/IN2018/050237, filed on Apr. 19, 2018.
Claims priority of application No. 201621035967 (IN), filed on Apr. 20, 2017; and application No. 201721045003 (IN), filed on Dec. 14, 2017.
Prior Publication US 2022/0389046 A1, Dec. 8, 2022
Int. Cl. C07H 15/26 (2006.01); A61P 35/00 (2006.01); C07D 311/48 (2006.01); C07D 317/50 (2006.01); C07D 405/04 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 407/04 (2006.01); C07D 407/12 (2006.01); A61K 31/357 (2006.01); A61K 31/4709 (2006.01); C07C 1/00 (2006.01); A61K 31/7048 (2006.01); A61K 31/10 (2006.01); A61K 31/4025 (2006.01); C07D 317/56 (2006.01)
CPC C07H 15/26 (2013.01) [A61K 31/10 (2013.01); A61K 31/357 (2013.01); A61K 31/4025 (2013.01); A61K 31/4709 (2013.01); A61K 31/7048 (2013.01); A61P 35/00 (2018.01); C07C 1/00 (2013.01); C07D 311/48 (2013.01); C07D 317/50 (2013.01); C07D 317/56 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 407/04 (2013.01); C07D 407/12 (2013.01)] 11 Claims
 
1. A compound of Formula IV:

OG Complex Work Unit Chemistry
R6 and R7 each independently is selected from —H, or alkoxy;
R is selected from:

OG Complex Work Unit Chemistry
R13 is —OH;
R14 is selected from alkoxy, or —OH;
R15 is selected from alkoxy, or —OH;
R16 is —H;
R17 is alkyl;
R11 and R12 each independently is selected from —H, substituted or unsubstituted 5-membered lactone ring, —C(O)O-alkyl;
when R is

OG Complex Work Unit Chemistry
R11 and R12 are not together as lactone; and
when R13 is —OH and, R14 and R15 are -alkoxy; then R16 is —H; R6, R7, R11 and R12 are not —H.