US 7,550,437 B2
Compositions for preventing and treating digestive organs diseases
Hiromasa Araki, Nara (Japan); Atsufumi Kawabata, Nara (Japan); Ryotaro Kuroda, Osaka (Japan); Kazuaki Kakehi, Nara (Japan); Shuichi Tanaka, Osaka (Japan); Kenzo Kawai, Osaka (Japan); Sachiyo Nishimura, Nara (Japan); and Hiroyuki Nishikawa, Nara (Japan)
Assigned to Fuso Pharmaceutical Industries, Ltd., Osaka (Japan)
Filed on Jan. 03, 2006, as Appl. No. 11/322,254.
Application 11/322254 is a division of application No. 10/204555, abandoned, previously published as PCT/JP01/01188, filed on Feb. 20, 2001.
Claims priority of application No. 2000-047515 (JP), filed on Feb. 24, 2000.
Prior Publication US 2006/0172949 A1, Aug. 03, 2006
Int. Cl. A61K 38/08 (2006.01)
U.S. Cl. 514—17 9 Claims
 
1. A method for decreasing gastric acid secretion by activating PAR-2, comprising administering to a patient in need thereof an effective amount of a peptide comprising at least one sequence selected from the group consisting of Ser-Leu-Ile-Gly-Arg-Leu-NH2 (SEQ ID NO: 1) and trans-cinnamoyl-Leu-Ile-Gly-Arg-Leu-ornithine-NH2 (SEQ ID NO: 2).