US 7,550,286 B2
Docosahexaenoic acid producing strains of Yarrowia lipolytica
Howard Glenn Damude, Hockessin, Del. (US); Daniel Joseph Macool, Philadelphia, Pa. (US); Stephen K. Picataggio, Landenberg, Pa. (US); James John Ragghianti, Bear, Del. (US); John E. Seip, Alloway, N.J. (US); Zhixiong Xue, Chadds Ford, Pa. (US); Narendra S. Yadav, Chadds Ford, Pa. (US); Hongxiang Zhang, Chadds Ford, Pa. (US); and Quinn Qun Zhu, West Chester, Pa. (US)
Assigned to E. I. du Pont de Nemours and Company, Wilmington, Del. (US)
Filed on Nov. 01, 2005, as Appl. No. 11/264,737.
Claims priority of provisional application 60/624812, filed on Nov. 04, 2004.
Prior Publication US 2006/0110806 A1, May 25, 2006
Int. Cl. C12N 1/16 (2006.01); C12P 7/64 (2006.01); C12N 9/02 (2006.01); C07H 21/04 (2006.01)
U.S. Cl. 435—254.2  [435/254.11; 435/134; 435/189; 536/23.2] 7 Claims
 
1. A recombinant production host cell for the production of docosahexaenoic acid further comprising at least one gene encoding Δ8 desaturase polypeptide having the amino acid sequence as set forth in SEQ ID NO: 78 or 82; wherein the production host is a Yarrowia sp.; and wherein the production host produces docosahexaenoic acid.