| US 7,550,258 B2 | ||
| Methods for drug discovery, disease treatment, and diagnosis using metabolomics | ||
| Rima Kaddurah-Daouk, Belmont, Mass. (US); and Bruce Kristal, White Plains, N.Y. (US) | ||
| Assigned to Metabolon, Inc., Durham, N.C. (US); and Cornell Research Foundation, Inc., Ithaca, N.Y. (US) | ||
| Filed on Apr. 14, 2006, as Appl. No. 11/405,033. | ||
| Application 11/405033 is a continuation of application No. 10/695265, filed on Oct. 27, 2003, granted, now 7,329,489. | ||
| Application 10/695265 is a continuation in part of application No. 09/835119, filed on Apr. 13, 2001, abandoned. | ||
| Claims priority of provisional application 60/421226, filed on Oct. 25, 2002. | ||
| Claims priority of provisional application 60/239340, filed on Oct. 11, 2000. | ||
| Claims priority of provisional application 60/239541, filed on Oct. 10, 2000. | ||
| Claims priority of provisional application 60/197117, filed on Apr. 14, 2000. | ||
| Claims priority of provisional application 60/197085, filed on Apr. 14, 2000. | ||
| Prior Publication US 2007/0072203 A1, Mar. 29, 2007 | ||
| This patent is subject to a terminal disclaimer. | ||
| Int. Cl. C12Q 1/00 (2006.01) | ||
| U.S. Cl. 435—4 [424/9.1; 424/9.2; 435/71; 436/518; 436/528] | 8 Claims |
| 1. A method for identifying small molecules relevant to a disease state, comprising:
obtaining a small molecule profile from a biological sample from a subject suffering from said disease state; and
comparing the small molecule profile from the subject to a standard small molecule profile, thereby identifying small molecules
relevant to said disease state, wherein said small molecule profile is obtained using one or more techniques which detect
50% or more of the small molecules in said sample.
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