| US 7,547,471 B2 | ||
| Material for implantation | ||
| Lars M. Bjursten, Limhamn (Sweden); and John A. Frangos, La Jolla, Calif. (US) | ||
| Assigned to La Jolla Bioengineering Institute, La Jolla, Calif. (US) | ||
| Appl. No. 10/503,405 PCT Filed Jan. 31, 2003, PCT No. PCT/SE03/00163 § 371(c)(1), (2), (4) Date Jul. 30, 2004, PCT Pub. No. WO03/063925, PCT Pub. Date Aug. 07, 2003. |
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| Claims priority of application No. 0200269 (SE), filed on Jan. 31, 2002. | ||
| Prior Publication US 2005/0074602 A1, Apr. 07, 2005 | ||
| Int. Cl. A61F 2/02 (2006.01); B32B 27/00 (2006.01); B32B 27/40 (2006.01); B32B 27/32 (2006.01) | ||
| U.S. Cl. 428—195.1 [424/400; 424/421; 424/422; 424/423; 427/2.27; 604/382; 428/334; 428/423.1; 428/447; 428/523; 623/11.11] | 7 Claims |
| 1. An implant comprising:
a sensor having a permeable membrane; and
a plurality of spaced apart patches of titanium dioxide disposed on the permeable membrane, each patch having a distance of
separation from its nearest adjacent patch, the distance of separation being from about 10 nm to about 10 μm,
wherein the permeable membrane allows the exchange of a molecule to be monitored by the sensor.
|