| US 7,545,495 B2 | ||
| Methods for visualizing crystals and distinguishing crystals from other matter within a biological sample | ||
| Kerry M. Swift, Libertyville, Ill. (US); and Edmund D. Matayoshi, Richmond, Ill. (US) | ||
| Assigned to Abbott Laboratories, Abbott Park, Ill. (US) | ||
| Filed on Dec. 29, 2005, as Appl. No. 11/321,993. | ||
| Application 11/321993 is a continuation in part of application No. 10/832748, filed on Apr. 27, 2004, abandoned. | ||
| Prior Publication US 2006/0215156 A1, Sep. 28, 2006 | ||
| Int. Cl. G01J 3/30 (2006.01); G01J 3/44 (2006.01) | ||
| U.S. Cl. 356—317 [356/301] | 14 Claims |
| 1. A method of distinguishing a crystal from other matter within a biological sample comprising the steps of:
a) exposing said biological sample to ultraviolet radiation (UV);
b) detecting radiation emission from said exposed biological sample, wherein said emission is luminescence comprising fluorescence,
polarized fluorescence or phosphorescence; and
c) analyzing said emission of step b) by determining whether 1) said emission of said biological sample has changed in comparison
to a sample comprising no crystal or 2) whether variations in said emission of said biological sample are greater than said
sample comprising no crystal, said change or variations allowing said crystal to be distinguished from other matter within
said biological sample.
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