US 7,544,671 B2
Stabilized hyaluronan preparations and related methods
Hampar L. Karageozian, San Juan Capistrano, Calif. (US); and John Park, Santa Ana, Calif. (US)
Assigned to S.K. Pharmaceuticals, Inc., San Juan Capistrano, Calif. (US)
Filed on May 09, 2005, as Appl. No. 11/126,075.
Claims priority of provisional application 60/569407, filed on May 07, 2004.
Prior Publication US 2006/0029571 A1, Feb. 09, 2006
Int. Cl. A01N 43/04 (2006.01); A61K 31/715 (2006.01)
U.S. Cl. 514—54  [514/23; 514/62] 28 Claims
 
1. A composition comprising hyaluronan having an average molecular weight in the range of about 2×103 to about 5×106 Daltons in combination with a polyglycol having an average molecular weight in the range of about 6000 to about 8000 Daltons in an amount which prevents the viscosity of the composition from decreasing substantially over a period of at least 2 years when stored in a closed container at room temperature.