| US 7,544,656 B2 | ||
| Long acting injectable insulin composition and methods of making and using thereof | ||
| Vladimir Sabetsky, Saint-Petersburg (Russian Federation) | ||
| Assigned to The Technology Development Company, Ltd., (Luxembourg) | ||
| Filed on Mar. 04, 2004, as Appl. No. 10/792,383. | ||
| Claims priority of provisional application 60/495097, filed on Aug. 15, 2003. | ||
| Claims priority of provisional application 60/469017, filed on May 09, 2003. | ||
| Claims priority of provisional application 60/467601, filed on May 05, 2003. | ||
| Claims priority of provisional application 60/451245, filed on Mar. 04, 2003. | ||
| Prior Publication US 2004/0234616 A1, Nov. 25, 2004 | ||
| Int. Cl. A61K 38/28 (2006.01) | ||
| U.S. Cl. 514—3 [424/400; 436/529; 514/59; 524/54] | 10 Claims |
| 1. A method of making a pharmaceutical composition suitable for injection into the body of a mammal, said method comprising:
providing crystallized dextran microparticles that do not include insulin; and
combining the crystallized dextran microparticles with insulin in an amount effective to lower the blood glucose level of
said mammal.
|