US 7,540,963 B2
Ultrafiltration membrane, device, bioartificial organ, and methods
William H. Fissell, IV, Ann Arbor, Mich. (US); H. David Humes, Ann Arbor, Mich. (US); Shuvo Roy, Cleveland, Ohio (US); and Aaron Fleischman, University Heights, Ohio (US)
Assigned to The Regents of the University of Michigan, Ann Arbor, Mich. (US); and The Cleveland Clinic Foundation, Cleveland, Ohio (US)
Filed on May 19, 2006, as Appl. No. 11/437,905.
Application 11/437905 is a continuation of application No. 10/660056, filed on Sep. 11, 2003, granted, now 7,048,856.
Claims priority of provisional application 60/409810, filed on Sep. 11, 2002.
Prior Publication US 2006/0213836 A1, Sep. 28, 2006
This patent is subject to a terminal disclaimer.
Int. Cl. B01D 71/00 (2006.01); C12N 5/00 (2006.01); A61B 5/05 (2006.01)
U.S. Cl. 210—645  [210/243; 210/321.72; 210/500.22] 21 Claims
OG exemplary drawing
 
1. An ultrafiltration system comprising:
a) a membrane comprising micromachined pores having a length and a width, said length being less than 200 microns and said width being less than 200 nanometers, wherein the ratio of said length to said width is at least 5:1;
b) a housing containing said membrane, wherein said housing comprises a coating, said coating being biocompatible for in vivo use; and
c) a fluid delivery passageway with a first end and a second end, said first end positioned outside of said housing, said second end positioned to delivery fluid across said membrane.