US 7,538,859 B2
Methods and systems for monitoring and obtaining information of at least one portion of a sample using conformal laser therapy procedures, and providing electromagnetic radiation thereto
Guillermo J. Tearney, Cambridge, Mass. (US); Milen Shishkov, Watertown, Mass. (US); Brett Eugene Bouma, Quincy, Mass. (US); and Benjamin J. Vakoc, Cambridge, Mass. (US)
Assigned to The General Hospital Corporation, Boston, Mass. (US)
Filed on Feb. 01, 2007, as Appl. No. 11/670,058.
Claims priority of provisional application 60/764622, filed on Feb. 01, 2006.
Claims priority of provisional application 60/810445, filed on Jun. 01, 2006.
Prior Publication US 2007/0177152 A1, Aug. 02, 2007
Int. Cl. G01L 1/24 (2006.01)
U.S. Cl. 356—35.5 25 Claims
OG exemplary drawing
 
1. A process for obtaining information associated with at least one portion of a biological sample, comprising:
receiving at least one first electro-magnetic radiation provided from a section near or in the at least one portion of the biological sample; and
identifying a deformation of the section at a plurality of depths as a function of at least one temperature change within the section and at least one of (i) a phase of at least one second electro-magnetic radiation provided from the section, or (ii) a rate of change of at least one of the phase or an amplitude of the at least one second electro-magnetic radiation.