US 7,538,096 B2
Treatment and prevention of abnormal cellular proliferation
Charles A. Hales, Lincoln, Mass. (US); Hari G. Garg, Belmont, Mass. (US); Lunyin Yu, Allston, Mass. (US); and Robert J Linhardt, Albany, N.Y. (US)
Assigned to The General Hospital Corporation, Boston, Mass. (US); and The University of Iowa Research Foundation, Iowa City, Iowa (US)
Filed on Mar. 16, 2005, as Appl. No. 11/82,213.
Claims priority of provisional application 60/553800, filed on Mar. 16, 2004.
Prior Publication US 2005/0288251 A1, Dec. 29, 2005
Int. Cl. A61K 31/727 (2006.01)
U.S. Cl. 514—56  [514/54; 536/21] 4 Claims
 
1. A method of treating a malignancy or cancer of the colon comprising: providing an effective amount of an O-acylated heparin near or into a site of a tumor of the colon, to thereby decrease in size, or cease the growth of the malignancy or cancer of the colon.