US 7,537,911 B2
	ATM related kinase, ATX, nucleic acids encoding same and methods of use
Robert T. Abraham, San Diego, Calif. (US); and Diane M. Otterness, San Diego, Calif. (US)
Assigned to Burnham Institute for Medical Research, La Jolla, Calif. (US); and Duke University, Durham, N.C. (US)
Filed on Apr. 17, 2007, as Appl. No. 11/788,003.
Application 11/788003 is a division of application No. 11/643551, filed on Dec. 20, 2006, granted, now 7,217,551.
Application 11/643551 is a division of application No. 10/456238, filed on Jun. 06, 2003, granted, now 7,166,716.
Claims priority of provisional application 60/813607, filed on Jun. 06, 2002.
Prior Publication US 2008/0166713 A1, Jul. 10, 2008
Int. Cl. C12Q 1/48 (2006.01)

U.S. Cl. 435—15

6 Claims

1. A method for identifying an ATX-modulatory compound, comprising measuring the level of an ATX polypeptide comprising the amino acid sequence as SEQ ID NO:2 in the presence of a test compound, wherein a difference in the level of that said ATX polypeptide in the presence of said test compound compared to in the absence of that said test compound indicating that said test compound is an ATX-modulatory compound, and wherein said ATX-modulatory compound is not caffeine or wortmannin.