| US 7,531,669 B2 | ||
| Methods for treating neural disorders and conditions, and compounds useful therefor | ||
| David R. Schubert, La Jolla, Calif. (US); Yuanbin Liu, San Diego, Calif. (US); and Thomas Baiga, San Marcos, Calif. (US) | ||
| Assigned to The Salk Institute for Biological Studies, La Jolla, Calif. (US) | ||
| Filed on Dec. 30, 2005, as Appl. No. 11/323,987. | ||
| Application 11/323987 is a continuation in part of application No. PCT/US2004/021399, filed on Jul. 02, 2004. | ||
| Claims priority of provisional application 60/484942, filed on Jul. 03, 2003. | ||
| Prior Publication US 2006/0160812 A1, Jul. 20, 2006 | ||
| Int. Cl. C07D 231/10 (2006.01); C07D 231/12 (2006.01) | ||
| U.S. Cl. 548—375.1 [548/376.1; 548/377.1] | 21 Claims |
1. A compound comprising the structure corresponding to Formula (II):
 m is 1,
n is 1,
X1 is N or NR3,
X2 is N or NR3,
X4 is CH,
one R is -L1-Ar1,
one R is -L2-Ar2,
L1 and L2 are —CH═CH—,
Ar1 and Ar2 are independently selected from the group consisting of phenyl, 4-hydroxyphenyl, 3-hydroxyphenyl, 3,4-dihydroxyphenyl and
3-methoxy, 4-hydroxy phenyl, and
R3 is selected from the group consisting of phenyl, isobutyl, 2-fluorophenyl, 3-fluorophenyl, 4-fluorophenyl, 3-nitrophenyl,
4-methoxyphenyl, 4-trifluoromethylphenyl, and 2,5-difluorophenyl.
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