US 7,531,541 B2
Partial mGluR5 antagonists for treatment of anxiety and CNS disorders
P. Jeffrey Conn, Brentwood, Tenn. (US); Alice L. Rodriguez, Nashville, Tenn. (US); and Carrie K. Jones, Nashville, Tenn. (US)
Assigned to Vanderbilt University, Nashville, Tenn. (US)
Filed on Sep. 20, 2006, as Appl. No. 11/523,873.
Claims priority of provisional application 60/718298, filed on Sep. 20, 2005.
Claims priority of provisional application 60/742516, filed on Dec. 06, 2005.
Prior Publication US 2007/0208028 A1, Sep. 06, 2007
Int. Cl. A61K 31/497 (2006.01); C07D 239/42 (2006.01)
U.S. Cl. 514—252.1  [514/256] 22 Claims
 
1. A partial, non-competitive mGluR5 antagonist compound for the treatment of conditions and disorders for which full mGluR5 antagonists are effective.