wherein each R1, R2 and R3 is independently selected from the group consisting of H and halogen;

A is selected from the group consisting of H and alkyl;

W is selected from the group consisting of NH and O;

D is selected from O, NH and S;

E is (—C(O)—)_p—R′, wherein p is 0 or 1 and R′ is selected from the group consisting of optionally substituted rings selected from phenyl, furanyl, pyridinyl, pyridinyl-N-oxide, pyrimidinyl, pyridazinyl, pyrazinyl, thiazolyl, triazinyl, thiadiazolyl, oxazolyl, isoxazolyl, thienopyrimidinyl, and pyrimidine fused with an aromatic or heteroaromatic ring selected from benzene, oxazole, isoxazole, furan, thiazole, pyrimidine, pyridine, pyrrole, pyrazine;

each ring being optionally substituted with one or more substituents selected from the group consisting of alkyl, alkenyl, alkynyl, halogen, haloalkyl, alkoxy, haloalkoxy, nitro, cyano, alkylsulfonyl, alkylsulfoxide, alkylthio, alkoxyiminoalkyl, alkylcarbonyl, alkoxycarbonyl, aminocarbonyl, hydroxycarbonyl, phenylcarbonyl, formyl, hydrazidocarbonyl, amidoamino, pyrazolyl, triazolonyl, oxadiazolyl, phenyl, pyridinyl, and phenoxyalkyl;

B is selected from the group consisting of halogen, alkyl, haloalkyl, alkoxy and haloalkoxy;

n is an integer from 0 to 3; and

m is an integer from 0 to 4

with the proviso that: when D is O or S and R′ is phenyl, then R′ is not further substituted with halogen or haloalkyl, and when D is O and R′ is thienopyrimidinyl the R′ is not further substituted with alkyl.