US 7,531,170 B1
Methods of treating OX40 mediated recall immune responses and agents useful for identifying same
Michael Croft, San Diego, Calif. (US); and Shahram Salek-Ardakani, San Diego, Calif. (US)
Assigned to La Jolla Institute for Allergy and Immunology, La Jolla, Calif. (US)
Filed on Sep. 07, 2006, as Appl. No. 11/518,364.
Application 11/518364 is a division of application No. 10/661358, filed on Sep. 11, 2003, granted, now 7,291,331.
Claims priority of provisional application 60/410534, filed on Sep. 11, 2002.
Int. Cl. A61K 39/395 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01)
U.S. Cl. 424—130.1  [530/387.1] 40 Claims
 
1. A method of reducing or inhibiting a recall immune response, wherein the recall response is associated with or causes asthma comprising administering an amount of an antibody or fragment thereof that binds to OX40 and reduces or inhibits OX40 signaling, expression or activity sufficient to reduce or inhibit a recall immune response.