| US 7,531,139 B2 | ||
| System for performing experiments, in particular for high throughput experimentation | ||
| Peter John van den Brink, Driebergen (Netherlands); Maarten Bracht, Amsterdam (Netherlands); and Bashir Husein Harji, Cottenham (United Kingdom) | ||
| Assigned to Avantium International B.V., Amsterdam (Netherlands) | ||
| Filed on Nov. 07, 2003, as Appl. No. 10/703,390. | ||
| Application 10/703390 is a continuation in part of application No. PCT/EP02/05321, filed on May 13, 2002. | ||
| Claims priority of provisional application 60/290031, filed on May 11, 2001. | ||
| Claims priority of application No. 01201739 (EP), filed on May 11, 2001. | ||
| Prior Publication US 2004/0115100 A1, Jun. 17, 2004 | ||
| This patent is subject to a terminal disclaimer. | ||
| Int. Cl. B01L 3/00 (2006.01) | ||
| U.S. Cl. 422—102 [422/104] | 14 Claims |
| 1. A system for performing experiments, in particular for high throughput experimentation, said system comprising:
at least one tubular vessel, said vessel having a first vessel opening and a second vessel opening at opposite ends thereof
allowing a flow of fluid through said vessel,
an assembly for housing said vessel, said assembly comprising:
a base block having a first face, a second face, and a first channel formed in said base block,
said first channel having a wall, a first opening, and a second opening, said first opening of said first channel extends
through said first face of the base block, and said second opening of the first channel extends through said second face of
the base block, said first and second openings of the first channel allowing introduction and/or discharge of a fluid into
and from said first channel,
a cover element having a bottom surface, the bottom surface extending over said first face of the base block and over the
first opening of the first channel, said bottom surface arranged adjacent and parallel to the first face of the base block;
a first sealing element arranged between the first face of the base block and the bottom surface of the cover element, the
first sealing element surrounding the first opening of the first channel completely, and thereby sealing gastight around said
first opening of the first channel between the cover element and the base block;
the wall of the first channel, the first sealing element, the bottom surface of the cover element and the second opening of
the first channel together delimiting a cavity, said tubular vessel being entirely accommodated in said cavity in such a way
that an annular gap is present between the tubular vessel and the wall of the first channel,
in which system a second sealing element is located in the first channel, said second sealing element sealing gastight against
the vessel and the wall-of the first channel, thereby sealing said annular gap; and
a fourth channel is provided in the base block, said fourth channel opens into the annular gap between the second sealing
element and the second vessel opening, and
a feed channel for feeding fluid into the cavity, which feed channel is in fluid communication with the cavity, the feed channel
being fluid communication with the second opening of the first channel via the tubular vessel.
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