US 7,530,259 B2
On-chip temperature controlled liquid chromatography methods and devices
Yu-Chong Tai, Pasadena, Calif. (US); Jun Xie, Pasadena, Calif. (US); Chi-yuan Shih, Pasadena, Calif. (US); and Qing He, Pasadena, Calif. (US)
Assigned to California Institute of Technology, Pasadena, Calif. (US)
Filed on Feb. 17, 2005, as Appl. No. 11/59,625.
Claims priority of provisional application 60/545727, filed on Feb. 17, 2004.
Prior Publication US 2005/0274174 A1, Dec. 15, 2005
Int. Cl. G01N 1/00 (2006.01); G01N 30/00 (2006.01)
U.S. Cl. 73—61.57  [73/61.52; 73/61.58] 16 Claims
OG exemplary drawing
 
1. An apparatus for liquid chromatography comprising a liquid chromatography separation column on a substrate, wherein the column is coupled to a heater on the substrate, wherein the substrate is silicon.