US 7,528,107 B2
	Methods of treating inflammation in mammalian tissues comprising administering human alpha-defensins
Jishu Shi, Auburn, Ala. (US); Shelly Aono, Auburn, Ala. (US); and Wuyuan Lu, Ellicott City, Md. (US)
Assigned to Auburn University, Auburn, Ala. (US)
Filed on Nov. 30, 2006, as Appl. No. 11/565,107.
Claims priority of provisional application 60/740991, filed on Nov. 30, 2005.
Prior Publication US 2008/0051333 A1, Feb. 28, 2008
Int. Cl. A01N 37/18 (2006.01); A61K 38/00 (2006.01)

U.S. Cl. 514—2  [514/12; 514/13]

6 Claims

1. A method for treating inflammation in mammalian tissues, said method comprising administering to a mammal in need thereof a human α-defensin in an amount effective to inhibit the posttranslational processing and release of interleukin-1 β.