dispensing a drug from a drug dispenser in response to an external drug delivery activation signal;

transmitting drug dispensation data to an implantable medical device in response to the drug dispensation;

acquiring data through the implantable medical device indicative of a response to the dispensed drug, wherein the data includes physiological data and device performance data, the device performance data comprising implantable medical device delivered electrical stimulation therapies and a response thereto; and

storing the drug dispensation data with the data acquired by the implantable medical device, the data acquired by the medical device grouped according to drug dispensation data.