| US 7,524,981 B2 | ||
| Phospholipid derivatives and process for the production there | ||
| Kazuhiro Kubo, Kanagawa (Japan); Chika Itoh, Kanagawa (Japan); Syunsuke Ohhashi, Kanagawa (Japan); Tohru Yasukohchi, Kanagawa (Japan); Yusuke Ohkawa, Kanagawa (Japan); Hiroshi Kikuchi, Tokyo (Japan); Norio Suzuki, Chiba (Japan); Miho Takahashi, Shizuoka (Japan); and Hitoshi Yamauchi, Tokyo (Japan) | ||
| Assigned to NOF Corporation, Tokyo (Japan); and DAIICHI Pharmaceutical Co., Ltd., Tokyo (Japan) | ||
| Appl. No. 10/541,309 PCT Filed Dec. 12, 2003, PCT No. PCT/JP03/15969 § 371(c)(1), (2), (4) Date Apr. 13, 2006, PCT Pub. No. WO2004/060899, PCT Pub. Date Jul. 22, 2004. |
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| Claims priority of application No. 2003-000330 (JP), filed on Jan. 06, 2003. | ||
| Prior Publication US 2006/0210618 A1, Sep. 21, 2006 | ||
| Int. Cl. C07C 9/02 (2006.01) | ||
| U.S. Cl. 554—78 [554/82; 424/450; 514/114] | 19 Claims |
1. A phospholipid derivative represented by the following formula (1):
 wherein [PG]k represents a residue of polyglycerin having a polymerization degree of k, wherein k is 2 to 50, R1CO and R2CO independently represent an acyl group having 8 to 22 carbon atoms, symbol “a” independently represents an integer of 0
to 5, symbol “b” independently represents 0 or 1, M represents hydrogen atom, an alkali metal atom, an ammonium, or an organic
ammonium, and k1, k2, and k3 represent numbers satisfying the following conditions: 1≤k1≤(k+2)/2, 0≤k2, and k1+k2+k3=k+2.
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