US 7,524,949 B2
Double stranded DNA inhibitor of IRF-1 activity
Markus Hecker, Göttingen (Germany); and Andreas H. Wagner, Göttingen (Germany)
Assigned to Avontec GmbH, Gottingen (Germany)
Appl. No. 10/398,592
PCT Filed Oct. 04, 2001, PCT No. PCT/DE01/03835
§ 371(c)(1), (2), (4) Date Oct. 02, 2003,
PCT Pub. No. WO02/29044, PCT Pub. Date Apr. 11, 2002.
Claims priority of application No. PCT/DE01/03835 (EP), filed on Oct. 04, 2001.
Prior Publication US 2004/0048820 A1, Mar. 11, 2004
Int. Cl. C07H 21/04 (2006.01); A61K 31/70 (2006.01)
U.S. Cl. 536—24.5  [536/23.1; 514/44] 2 Claims
 
1. An inhibitor of IRF-1 activity, wherein the inhibitor is a double-stranded DNA molecule having a length of 18 to 23 base pairs and comprising the sequence of SEQ ID NO:11 in one strand and SEQ ID NO:12 in the complementary strand.